Every time a poet writes a poem it’s like it’s the first time. When you’ve finished a poem, you don’t know if you’ll ever write another one. Some poems arrive with a weight that’s more significant than other poems and you know it will take a lot of care to do it justice. Poetry, for so long now, has been the way I relate to everything. It’s like a companion. I can’t imagine ever being separated from it.

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Women's sexy underwear is a minor but significant growth industry of late-twentieth-century Britain in the twilight of capitalism.

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If we could sniff or swallow something that would, for five or six hours each day, abolish our solitude as individuals, atone us with our fellows in a glowing exaltation of affection and make life in all its aspects seem not only worth living, but divinely beautiful and significant, and if this heavenly, world-transfiguring drug were of such a kind that we could wake up next morning with a clear head and an undamaged constitution -- then, it seems to me, all our problems (and not merely the one small problem of discovering a novel pleasure) would be wholly solved and earth would become paradise.

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When the frustration of my helplessness seemed greatest, I discovered God's grace was more than sufficient. And after my imprisonment, I could look back and see how God used my powerlessness for His purpose. What He has chosen for my most significant witness was not my triumphs or victories, but my defeat.

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What was significant about the laughter . . . was not just the fact that it provides internal exercise for a person . . .a form of jogging for the innards, but that it creates a mood in which the other positive emotions can be put to work, too.

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In the short run, the 'federalism revolution' of the 1990s is undeniably his most significant substantive achievement. But whether these rulings will survive in the long run, or instead be reversed, remains to be seen. It's much more likely that the Rehnquist Court's surprisingly liberal rulings -- on abortion, on gay rights, on gender -- will actually represent the most indelible legacy.

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At two-tenths the speed of light, dust and atoms might not do significant damage even in a voyage of 40 years, but the faster you go, the worse it is--space begins to become abrasive. When you begin to approach the speed of light, hydrogen atoms become cosmic-ray particles, and they will fry the crew. ...So 60,000 kilometers per second may be the practical speed limit for space travel.

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We need to get cancer patients near treatment and keep them near their families at the same time. These three mobile homes are only the beginning. With the help of others in the mobile home and transportation industries, we hope to make a significant impact on the lives of people with cancer in the Gulf Region.

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A significant number of Casey supporters still do not know that Casey is opposed to abortion. There are a significant number of pro-choice voters whose entire opinion swings on that one issue, and, unlike other single-issue voters, they will use their vote on just that one issue, even if it hurts the candidate they are otherwise philosophically attuned with.

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The stereotypical belief that large numbers of employees are 'going postal' is a bit of a myth. Interestingly, workers pinpoint the general public as the most significant source of this aggression, as opposed to other co-workers or supervisors.

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Never deceive the media or the public. Credibility is all we have to go on. Nothing gets done without total commitment and outrage mixed with political realism. Never assume anything: Check everything out yourself, at the source. Establish the credibility that when we start something, we finish it. With such track record, we then move to bigger struggles and more significant victories. No congressional bill or legal gimmickry by itself will save the animals. The courts can, at best, open up the possibility for us to intervene in defense of animals, but the courts will not act until effective protests disrupt the system's orderly operation.

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There are fine things which you mean to do some day, under what you think will be more favorable circumstances. But the only time that is surely yours is the present, hence this is the time to speak the word of appreciation and sympathy, to do the generous deed, to forgive the fault of a thoughtless friend, to sacrifice self a little more for others. Today is the day in which to express your noblest qualities of mind and heart, to do at least one worthy thing which you have long postponed, and to use your God-given abilities for the enrichment of someone less fortunate. Today you can make your life - significant and worthwhile. The present is yours to do with as you will.

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There has been a significant backsliding on human rights and we are seeing that principally in terms of increasing restrictions on what it's possible to say in the press -- certainly what it's possible to say on the Internet.

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The NCAA executive committee continues to believe the stereotyping of Native Americans is wrong. However, in its review of the particular circumstances regarding Florida State, the staff review committee noted the unique relationship between the university and the Seminole Tribe of Florida as a significant factor.

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[After failing to find any evidence of that, Wilson wrote a newspaper article, in which he accused the Bush administration of] exaggerating the Iraqi threat ... Saddam Hussein recently sought significant quantities of uranium from Africa.

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I think for the road we've traveled this is a significant achievement for our kids. The way we've been able to get to this moment has been to stay focused and take things as they come. Hopefully they will feel honored and deserving and keep it in perspective.

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One might have thought that the most significant change in the film industry that would come about with a transition from the communist economy to capitalism would fundamentally concern the sources of funding.

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With few new drugs coming through the pipeline, significant investment is required to build a pipeline sufficient to support future growth, especially in light of patent expiries in 2007-9. Nevertheless, we see significant share price downside as unlikely.

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The capacity for hope is the most significant fact of life. It provides human beings with a sense of destination and the energy to get started.

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This was a very competitive group of entries. The judging was tremendously difficult. Each of the entries explored the power of Revenue Optimization techniques to generate significant cash flow and improved earnings under diverse circumstances. However, the winning entry demonstrated a very real and immediate potential to revolutionize the $200 billion fashion industry.

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I believe the single most significant decision I can make on a day-to-day basis is my choice of attitude. It is more important than my past, my education, my bankroll, my successes or failures, fame or pain, what other people think of me or say about me, my circumstances, or my position. Attitude keeps me going or cripples my progress. It alone fuels my fire or assaults my hope. When my attitudes are right, there is no barrier too high, no valley too deep, no dream too extreme, no challenge too great for me.

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The launch of a one-time-use digital still and video cameras truly makes digital memory capture available to the entire mass market for the first time. Our alliance with Pure Digital has enabled us to open up a significant market for Samsung memory and storage solutions.

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I have been photographing our toilet, that glossy enameled receptacle of extraordinary beauty. Here was every sensuous curve of the human figure divine but minus the imperfections. Never did the Greeks reach a more significant consummation to their culture, and it somehow reminded me, in the glory of its chaste convulsions and in its swelling, sweeping, forward movement of finely progressing contours, of the Victory of Samothrace.

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Every American, to the last man, lays claim to a "sense" of humor and guards it as his most significant spiritual trait, yet rejects humor as ...

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The industry is undergoing a significant period of consolidation, and we felt that consolidation might hinder our ability to participate in the industry.

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It's the reason why I started 13 years ago on this quest, to win a championship. Along the way, I amassed a lot of yards, a lot of Pro Bowls, but none of that was significant because it wasn't the team goal.

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Letters are among the most significant memorial a person can leave behind them.

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Later that day I got to thinking about relationships. There are those that open you up to something new and exotic, those that are old and familiar, those that bring up lots of questions, those that bring you somewhere unexpected, those that bring you far from where you started, and those that bring you back. But the most exciting, challenging and significant relationship of all is the one you have with yourself. And if you can find someone to love the you you love, well, that's just fabulous.

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If the most significant characteristic of man is the complex of biological needs he shares with all members of his species, then the best lives for the writer to observe are those in which the role of natural necessity is clearest, namely, the lives of the very poor.

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In terms of human health, the predominant risk is poultry because that is where there is significant exposure to the human population. The direct risk of migrating birds (infecting) humans is negligible -- it's like being knocked down by a bus.

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