If we knew what it was we were doing, it would not be called research, would it?
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In an earlier stage of our development most human groups held to a tribal ethic. Members of the tribe were protected, but people of other tribes could be robbed or killed as one pleased. Gradually the circle of protection expanded, but as recently as 150 years ago we did not include blacks. So African human beings could be captured, shipped to America and sold. In Australia white settlers regarded Aborigines as a pest and hunted them down, much as kangaroos are hunted down today. Just as we have progressed beyond the blatantly racist ethic of the era of slavery and colonialism, so we must now progress beyond the speciesist ethic of the era of factory farming, of the use of animals as mere research tools, of whaling, seal hunting, kangaroo slaughter and the destruction of wilderness. We must take the final step in expanding the circle of ethics.
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It is in fact hard to find a single, common solid neoplasm [cancer] where management and expectation of cure has been markedly affected by animal research. Most human cancers differ from the artificially produced animal model
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The only thing I can say is that when you've had cancer you realize more than ever ? even though you should probably realize it before ? how important raising money for research is. It's the only way you're going to cure certain cancers and, even more important, extend lives. It was 1999 when I was diagnosed. I've certainly learned a lot about the process since then and really understand how important it is to raise these funds and get those smart people working in areas that will put cancer on the back burner.
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I was raised on a dairy farm and ate plenty of meat and eggs until about twenty years ago. I started doing nutritional research, and a decade or so after that my family made some major dietary changes. I'm just paying attention to what the data are telling me. The scientific evidence came first.
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Animal model systems in cancer research have been a total failure…not a single essential drug for the treatment of human cancer was first picked up by an animal model system. All of the drugs in wide current clinical use were only put into animal model systems after finding clinical clues to their therapeutic possibility. The money was spent…for two main reasons. First, it was a highly profitable undertaking for certain medical schools and research institutions that were incapable of doing any genuine cancer research. Second, it was sustained by a superstitious belief in a grossly unscientific notion: mice are miniature men…in sum, from the standpoint of current scientific theory of cancer, the whole mystique of the animal model systems is hardly more than superstitious nonsense…the moral is that animal model systems not only kill animals, they also kill humans. There is no good factual evidence to show the use of animals in cancer research has led to the prevention or cure of a single human cancer.
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The fundamental problem in drug discovery for cancer is that the model systems are not predictive at all. ancer research at Merck Research Laboratories in West Point, Pennsylvania…Researchers blamed the failures on the fact that the drugs were being tested against mouse, not human, tumors… the xenograft tumors don't behave like naturally occurring tumors in humans – they don't spread to other tissues, for example. Thus, drugs tested in the xenografts appeared effective but worked poorly in humans.
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What we demand is integrity and honesty of the research that is rendered,
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Brain research tells us that only twenty percent of human beings have a sense of irony, which means that eighty percent of the world takes everything at face value.
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It is a good morning exercise for a research scientist to discard a pet hypothesis every day before breakfast. It keeps him young.
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The question grows more troubling with each passing year how much of what yesterday's science fiction regarded as unspeakably dreadful has become today's award-winning research
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No religious organization must be allowed to impose its biased views on the rest of us about what they consider to be proper morality, education, sexual behavior, marriage, divorce, birth control, abortion, stem cell research by legislating their private prejudices on the rest of us.
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My own medical perspective is that animal cancer research should be regarded as the scientific equivalent of gossip – with about the same chance of turning out to be true, i.e. truly effective in humans. Some gossip turns out to be true, but most of it does not…and gossip can cause great anguish for those affected, in this case millions of desperate cancer patients worldwide.
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It is difficult to describe in short the enthusiasm and devotion provoked by and given to my research. We lived almost in poverty. I used pencils, two for a nickel, and could not buy a fountain pen, when I lost mine.
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Animal research was NOT responsible for the development of coronary bypass surgery. In 1961 in France, Kunlin first used a portion of a person's own vein to replace obstructed arterial segments. This gave birth to arterial bypass surgery for different parts of the body, the heart included. By contrast, Beck of Ohio and Vineburg of Canada took their theories to the animal laboratory in search of surgical answer to the complications of coronary artery disease. Each devised more than one procedure, envisioning success from their findings in animals. Not long after, their recommended operations were performed on thousands of human patients. What were the results? To say the least, unworthy. To put it bluntly; a fiasco, a total failure. I am witness to this event and the least I can do is speak out. Animal experimentation inevitably leads to human experimentation. That is the final verdict, sad as it is. And the toll mounts on both sides.'
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We don't believe that threats and pressure, including using the UN Security Council, will make Iran relinquish its legitimate rights [to peaceful nuclear energy]. Nuclear research activities are continuing.
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Who's most likely to buy our products, who's least likely to buy them and who's up for grabs. This has given us a much deeper insight than we've ever had before using traditional demographic or vehicle segment-based models. One of the most important findings from this research is that there remains a huge market for American cars in this country. And the potential is significantly larger than the roughly 55 percent market share than GM, Ford and Chrysler together command today.
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What is research, but a blind date with knowledge.
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Dogs have been extensively used in heart research, but their coronary arteries differ from those of humans - they have smaller connections with one another and the left coronary artery dominates, while in humans the right does so. In addition, the conduction system has a different pattern of blood supply, and consequently, researchers have had difficulty in producing ischemic heart blocks in dogs, which occurs frequently in humans. The blood coagulation mechanism is unlike ours, therefore using dogs to test prosthetic devices and valves is unreliable. A dog's reaction to shock is also very different to that of humans.
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Less than ten per cent of cancer research funding goes to early detection. Our emphasis is on collaboration across technologies and institutions. We have assembled some of the world's leading researchers, including Dr. Brad Nelson from the BC Cancer Agency, to attack early detection in a new collaborative approach.
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Although leadership and the exercise of power are distinguishable activities, they overlap and interweave in important ways. Consider a corporate chief executive officer who has the gift for inspiring and motivating people, who has vision, who lifts the spirits of employees with a resulting rise in productivity and quality of product, and a drop in turnover and absenteeism. That is leadership. But evidence emerges that the company is falling behind in the technology race. One day with the stroke of a pen the CEO increases the funds available to the research division. That is the exercise of power. The stroke of a pen could have been made by an executive with none of the qualities one associates with leadership.
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To support federal funding for embryonic stem cell research is to come down on the side of hope for the millions of Americans suffering from diseases ranging from Alzheimer's to cancer to Parkinson's to diabetes,
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If you're teaching a class, you can think about the elementary things that you know very well. These things are kind of fun and delightful. It doesn't do any harm to think them over again. Is there a better way to present them? The elementary things are easy to think about; if you can't think of a new thought, no harm done; what you thought about it before is good enough for the class. If you do think of something new, you're rather pleased that you have a new way of looking at it. The questions of the students are often the source of new research. They often ask profound questions that I've thought about at times and then given up on, so to speak, for a while. It wouldn't do me any harm to think about them again and see if I can go any further now. The students may not be able to see the thing I want to answer, or the subtleties I want to think about, but they remind me of a problem by asking questions in the neighborhood of that problem. It's not so easy to remind yourself of these things.
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Recent research has revealed that birds are capable of complex cognition . . . it is now clear that birds have cognitive capacities equivalent to those of mammals, even primates . . . it should be realized that even vastly improved intensive systems are unlikely to meet the cognitive demands of the hitherto underestimated chicken brain. . . . With the increased knowledge of the behaviour and cognitive abilities of the chicken has come the realization that the chicken is not an inferior species to be treated merely as a food source.
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Research is creating new knowledge.
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The environment is worth more than consumer goods and the g.n.p. freedom of speech is absolute and inviolate. guns are too dangerous for private ownership. sustainable & non-polluting energy sources make environmental and economic sense. research performed on animals is, by definition, scientifically unsound. cruelty is unacceptable. what you do with your own body is your choice. one individual violently imposing his or her will on another individual is wrong. you can't expect people to worry about the world when they can't feed themselves or their children. the hazards and risks of nuclear power make it unacceptable as an energy source. the use of animals for food is unhealthy, inefficient, & cruel. people need love & affection. tobacco use has killed & harmed more people than all human wars combined.
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The great question that has never been answered and which I have not yet been able to answer, despite my 30 years of research into the feminine soul, is: What does a woman want?
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Humanity needs practical men, who get the most out of their work, and, without forgetting the general good, safeguard their own interests. But humanity also needs dreamers, for whom the disinterested development of an enterprise is so captivating that it becomes impossible for them to devote their care to their own material profit. A well-organized society should assure to such workers the efficient means of accomplishing their task, in a life freed from material care and freely consecrated to research.
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The larger research programs that the National Science Foundation and National Institutes of Health are sponsoring require a machine like this to manage such large amounts of data.
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'As for bypass surgery, animal research actually retarded this therapy for humans. Because a dog's clotting characteristics and coronary valves are so different from ours, the initial human patients died. The first success was Dr Kunlin's work in France. Dr Kunlin's work was clinical and had nothing to do with animal research.'---
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