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Famous Dr Trevor Powles Quotations

Best famous Dr Trevor Powles quotations. Find, read, and share the best famous quotations by Dr Trevor Powles. These are the most popular quotations and best examples of quotes by Dr Trevor Powles.

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Quote Left [Regarding tamoxifen, an anti-cancer drug] 'Experimentally, tamoxifen has carcinogenic potential. In some strains of rat, but not mouse or hamster, tamoxifen can cause liver cancers at doses as low as 5mg/kg per day... However, there are doubts about the correlation of [the results] with the risk of malignant disease even in rats, let alone in other rodents, mammals, or human beings. There are many uncertainties in extrapolating these experimental data from rats to women. The effect depends on bioavailability, hepatic [liver] blood flow, and hepatic [liver] metabolism to active genotoxic carcinogens, all of which differ enormously between rat and man. Quote Right

Book: Shattered Sighs