Dogs have been extensively used in heart research, but their coronary arteries differ from those of humans - they have smaller connections with one another and the left coronary artery dominates, while in humans the right does so. In addition, the conduction system has a different pattern of blood supply, and consequently, researchers have had difficulty in producing ischemic heart blocks in dogs, which occurs frequently in humans. The blood coagulation mechanism is unlike ours, therefore using dogs to test prosthetic devices and valves is unreliable. A dog's reaction to shock is also very different to that of humans.
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We stuck in all the symptoms that diabetics get, ranging from serious things like death to less serious things like ballooning of the arteries in the legs. While it didn't meet the goal at the combination endpoint, it did on the one that really matters to patients: death, heart attacks and strokes.
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Lest darkness fall and time fall In a long night when learned arteries...
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Along the iron veins that traverse the frame of our country, beat and flow the fiery pulses of its exertion, hotter and faster every hour. All vitality is concentrated through those throbbing arteries into the central cities; the country is passed over like a green sea by narrow bridges, and we are thrown back in continually closer crowds on the city gates.
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A man is as old as his arteries and his interests. If he permits his economic, religious, or social arteries to harden, or loses interest in whatever concerns mankind... he will need only six feet of earth.
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As the arteries grow hard, the heart grows soft.
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