[adj] fairly large; "won by a substantial margin"
[adj] rich in significance or implication; "a meaning look"; "pregnant with meaning"
[adj] important in effect or meaning; "a significant change in tax laws"; "a significant change in the Constitution"; "a significant contribution"; "significant details"; "statistically significant"
[adj] (statistics) too closely correlated to be attributed to chance and therefore indicating a systematic relation; "the interaction effect is significant at the .01 level"; "no significant difference was found"
big, considerable, earthshaking, epochal, epoch-making, evidential, evidentiary, fundamental, head(a), important, key, large, meaning(a), meaningful, momentous, monumental, noteworthy, operative, portentous, pregnant, probative, prodigious, profound, rema