Then, wearied by the uncertainty and difficulties with which each scheme appeared to be attended, he bent up his mind to the strong effort of shaking off his love, like dew-drops from the lion's mane, and resuming those studies and that career of life which his unrequited affection had so long and so fruitlessly interrupted. In this last resolution he endeavoured to fortify himself by every argument which pride, as well as reason, could suggest.
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The system -- the American one, at least -- is a vast and noble experiment. It has been polestar and exemplar for other nations. But from kindergarten until she graduates from college the girl is treated in it exactly like her brothers. She studies the same subjects, becomes proficient at the same sports. Oh, it is a magnificent lore she learns, education for the mind beyond anything Jane Austen or Saint Theresa or even Mrs. Pankhurst ever dreamed. It is truly Utopian. But Utopia was never meant to exist on this disheveled planet.
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...Women's Studies can amount simply to compensatory history; too often they fail to challenge the intellectual and political structures that ...
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Know thyself. A maxim as pernicious as it is ugly. Whoever studies himself arrest his own development. A caterpillar who seeks to know himself would never become a butterfly.
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The conscience of the world is so guilty that it always assumes that people who investigate heresies must be heretics; just as if a doctor who studies leprosy must be a leper.
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Gentlemen, you are now about to embark on a course of studies which will occupy you for two years. Together, they form a noble adventure. But I would like to remind you of an important point. Nothing that you will learn in the course of your studies will be of the slightest possible use to you in after life, save only this, that if you work hard and intelligently you should be able to detect when a man is talking rot, and that, in my view, is the main, if not the sole, purpose of education.
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My own participation in the campaign was delayed by the death of my son Calvin, which occurred on the seventh of July. He was a boy of much promise, proficient in his studies, with a scholarly mind, who had just turned sixteen. He had a remarkable insight into things. The day I became President he had just started to work in a tobacco field. When one of his fellow laborers said to him, if my father was President I would not work in a tobacco field, Calvin replied, If my father were your father, you would.... We do not know what might have happened to him under other circumstances, but if I had not been President, he would not have raised a blister on his toe, which resulted in blood poisoning, playing lawn tennis in the South Grounds.In his suffering he was asking me to make him well. I could not. When he went the power and the glory of the Presidency went with him. The ways of Providence are often beyond our understanding. It seemed to me that the world had need of the work that it was probable he could do. I do not know why such a price was exacted for occupying the White House.
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Studies indicate that the one quality all successful people have is persistence. They're willing to spend more time accomplishing a task and to perservere in the face of many difficult odds. There's a very positive relationship between people's ability to accomplish any task and the time they're willing to spend on it.
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Since its inception 25 years ago, EPA [the US Environmental Protection Agency] has applied the same logic to hundreds of other substances, extrapolating from high levels in animal studies to arrive at acceptable levels for humans. But that approach, say scientists both inside and outside the federal government, may no longer be the best way to safeguard public health...EPA's new emphasis on molecular data is based on a growing body of evidence that extrapolations from megadoses can provide a misleading picture of the effects of low-level exposure. Chloroform is a good example. EPA's current strict standards were derived from a study in which mice developed liver tumors after exposure to massive daily doses of chloroform pumped into their stomachs over several months. However, those findings may not be relevant to human exposures, according to a paper picked by the Society of Toxicology as the best published last year in its journal.
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Even the poor student studies and is taught only political economy, while that economy of living which is synonymous with philosophy is not ev...
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To give a child animal products is a form of child abuse. (child's diabetes related to cows' milk.) (His book Food For Life cites 300 dietary studies.)
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In addition to state-of-the-art 3D rendering techniques, Visage CS 2.0 now features hanging protocols and viewing comparison of multiple series/studies side by side, as well as vessel analysis and PET-CT protocols. Through the thin client technology, the full set of functions becomes available anywhere, anytime, for any number of users throughout the hospital enterprise, without requiring special hardware on the client side.
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If poetry is like an orgasm, an academic can be likened to someone who studies the passion-stains on the bedsheets.
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In the U.S. NCI retrospective (2001), activity in at least 33% of models of a variety of histologies predicted for clinical activity in some disease. In the NCI of Canada retrospective (2003), generally similar conclusions were reached. It should be cautioned, however, that the drugs used in these studies were for the most part 'classic' cytotoxics. Whether 'targeted' therapeutics, such as signal transduction inhibitors, antiangiogenic, or stroma-modifying agents, would perform better or worse remains to be defined.
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We're pleased that the Executive wants to widen access to higher education, but we need to make sure that they put in place the necessary support package to make sure students do not have to give up their studies for financial reasons.
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Read, read, read. Read everything-- trash, classics, good and bad, and see how they do it. Just like a carpenter who works as an apprentice and studies the master. Read! You'll absorb it. Then write. If it is good, you'll find out. If it's not, throw it out the window.
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Yes, I think it is very clear to all of us who are engaged in the business of assessing toxicity data that, when volumes of data are proudly presented to us after a carcinogenicity study, showing that there was a tumour in this organ or that, we look at it and we scratch our heads, and we wonder what on earth we can make of it. This is especially true when huge doses are given, with nothing to suggest what would be expected at low doses. I think very often the carcinogenicity studies are a waste of everybody's time and a fearful waste of animals. They are conducted partly because we are not sure what to do instead, and partly because they are a political gesture and a very miserable one at that.
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Why the dog was ever considered as an appropriate animal for carcinogenicity testing is also not entirely clear... Despite the obvious problems of study design and interpretation, carcinogenicity tests in the dog, lasting 7 years, were requested by regulatory authorities from the late 1960s...One of the best known examples of the inappropriate use of the dog was the carcinogenicity testing of hormonal contraceptives. It is now understood that mammogenesis in the dog is very different from that in primates; quantitative and qualitative differences exist in the feedback control mechanisms, receptor content and behaviour, and target sensitivity and responsivity. As a result of this biological difference there was a high incidence of mammary tumours in long-term studies in dogs treated with progestagens/contraceptive steroids such as lynestrol. Ultimately pressure from the scientific community led, relatively recently, to the requirement for carcinogenicity studies in dogs being dropped.
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Elsewhere, I have pointed out that overfeeding of rats profoundly influences the incidence particularly of endocrine tumours. Furthermore, endocrine tumours and tumours of tissues, such as the breast and uterus, which are very directly under sex-hormone control, constitute a very high proportion of the tumours observed in most carcinogenicity studies in rats. [Comparing] the incidences of tumours in these categories in men and women with those in male and female rats... [shows] the differences between the two species are sufficiently striking to make one wonder how appropriate the laboratory rat is as a model for man in terms of the spectra of tumours to which they are prone.
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I am delighted to have you play football. I believe in rough, manly sports. But I do not believe in them if they degenerate into the sole end of any one's existence. I don't want you to sacrifice standing well in your studies to any over-athleticism and I need not tell you that character counts for a great deal more than either intellect or body in winning success in life. Athletic proficiency is a mighty good servant, and like so many other good servants, a mighty bad master.
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Devotees of grammatical studies have not been distinguished for any very remarkable felicities of expression.
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The principal method of determining potential carcinogenicity of substances is based on studies of daily administration of huge doses of chemicals to inbred rodents for a lifetime. Then by questionable models, which include large safety factors, the results are extrapolated to effects of minuscule doses in humans... The rodent MTD test that labels plant chemicals as cancer-causing in humans is misleading. The test is likewise of limited value for synthetic chemicals. The standard carcinogen tests that use rodents are an obsolescent relic of the ignorance of past decades.
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Your good article about causing serious questions when medical results on men studies are applied to women, opened my eyes: If men and women are so different, how in the world can scientists reach any valid conclusions from the myriad projects and experiments... on different species??? It makes all the animal testing/experimentation pretty futile!
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The standard carcinogenicity bioassay, which involves treating two rodent species for a minimum of 2 years, at a range of doses, is acknowledged to be an insensitive tool because of the background `noise' of spontaneous disease. Most strains of rat used in such studies have high incidence of pituitary and mammary tumours; some inbred rat strains frequently develop leukaemia or testicular tumours; mice strains show high incidence of malignant lymphomas and liver tumours.
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Results of the animal studies raise questions about the validity of federal regulations that are based on ad lib-fed inbred strains of rodents. Are humans to be regarded as behaving biochemically like huge, obese, inbred cancer-prone rodents?
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How very seldom do you encounter in the world a man of great abilities, acquirements, experience, who will unmask his mind, unbutton his brains, and pour forth in careless and picturesque phrase all the results of his studies and observation; his knowledge of men, books, and nature. On the contrary, if a man has by any chance an original idea, he hoards it as if it were old gold; and rather avoids the subject with which he is most conversant, from fear that you may appropriate his best thoughts.
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It were a real increase of human happiness, could all young men from the age of nineteen be covered under barrels, or rendered otherwise invisible; and there left to follow their lawful studies and callings, till they emerged, sadder and wiser, at the age of twenty-five.
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That even in its sharpest pangs of pain a dog can still caress its master we have learnt from the studies of vivisectors.
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There have been studies that clearly state that children who are exposed to arts education at a young age will in fact do markedly better in their SAT tests.
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We're building a whole public health strategy based on these drugs, extrapolating a huge amount from a few small studies. How could you say they are efficacious? We don't know. Given that governments are spending millions, it's unconscionable that companies aren't giving more answers.
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