The estimate made by NIOSH was 597 excess cancers per 10,000 workers having that same exposure... Instead of extra cancers predicted by NIOSH, workers had fewer cancers than expected...With trillions of dollars, loss of competitiveness, and jobs at stake, a searching review of the risk assessment methodology of the regulatory agencies is overdue.
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The function of government ought to be: make sure you have good water to drink, somebody picking up the garbage, good roads to drive on, enough electricity to turn your light bulbs and your record player on, and whatever smaller amounts of regulatory assistance is necessary to make this society work.
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Why the dog was ever considered as an appropriate animal for carcinogenicity testing is also not entirely clear... Despite the obvious problems of study design and interpretation, carcinogenicity tests in the dog, lasting 7 years, were requested by regulatory authorities from the late 1960s...One of the best known examples of the inappropriate use of the dog was the carcinogenicity testing of hormonal contraceptives. It is now understood that mammogenesis in the dog is very different from that in primates; quantitative and qualitative differences exist in the feedback control mechanisms, receptor content and behaviour, and target sensitivity and responsivity. As a result of this biological difference there was a high incidence of mammary tumours in long-term studies in dogs treated with progestagens/contraceptive steroids such as lynestrol. Ultimately pressure from the scientific community led, relatively recently, to the requirement for carcinogenicity studies in dogs being dropped.
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The current chaotic state of affairs where (small businesses) operated outside the regulatory framework and in undesignated and crime-ridden areas could not be countenanced for much longer,
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The function of government ought to be: make sure you have good water to drink, somebody picking up the garbage, good roads to drive on, enough electricity to turn your light bulbs and your record player on, and whatever smaller amounts of regulatory assi
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