Common-sense is part of the home-made ideology of those who have been deprived of fundamental learning, of those who have been kept ignorant. This ideology is compounded from different sources: items that have survived from religion, items of empirical knowledge, items of protective skepticism, items culled for comfort from the superficial learning that is supplied. But the point is that common-sense can never teach itself, can never advance beyond its own limits, for as soon as the lack of fundamental learning has been made good, all items become questionable and the whole function of common-sense is destroyed. Common-sense can only exist as a category insofar as it can be distinguished from the spirit of inquiry, from philosophy.
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In summary, mouse xenograft models should not be viewed as ideal models for cancer drug development. Altered, nonhuman host stroma, poor predictive value when applied in an empirical sense, and questionable relation to the naturally occurring human disease are but a few features, which temper enthusiasm for their use.
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Read not books alone, but men, and amongst them chiefly thyself. If thou find anything questionable there, use the commentary of a severe friend rather than the gloss of a sweet lipped flatterer; there is more profit in a distasteful truth than in deceitful sweetness.
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The principal method of determining potential carcinogenicity of substances is based on studies of daily administration of huge doses of chemicals to inbred rodents for a lifetime. Then by questionable models, which include large safety factors, the results are extrapolated to effects of minuscule doses in humans... The rodent MTD test that labels plant chemicals as cancer-causing in humans is misleading. The test is likewise of limited value for synthetic chemicals. The standard carcinogen tests that use rodents are an obsolescent relic of the ignorance of past decades.
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It is reserved for man alone to find his very existence questionable, to experience the whole dubiousness of being. More than such faculties as power of speech, conceptual thinking, or walking erect, this factor of doubting the significance of his own existence is what sets man apart from animal.
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Television hangs on the questionable theory that whatever happens anywhere should be sensed everywhere. If everyone is going to be able to see everything, in the long run all sights may lose whatever rarity value they once possessed, and it may well turn out that people, being able to see and hear practically everything, will be specially interested in almost nothing.
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Angels and ministers of grace defend us.Be thou a spirit of health, or goblin damned,Bring with thee airs from heaven, or blasts from hell,Be thy intents wicked, or charitable,Thou com'st in such a questionable shape,That I will speak to thee.
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Sometimes, his methods and his motives are questionable and even his morals are questionable in the way he does things. But I think his intention is always to protect his daughter.
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This spending of the best part of one's life earning money in order to enjoy a questionable liberty during the least valuable part of it remin...
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