Change is needed. Thirty years of experience with subcutaneous xenografts, human tumors implanted under the skin of the mouse, have satisfied few because so many drugs that cure cancer in these mice fail to help humans. A 2004 analysis in the Journal of the American Medical Association showed that only 3.8% of patients in phase I cancer drug trials between 1991 and 2002 achieved an objective clinical response — and the response rate is declining. Almost all drugs tried in humans work against subcutaneous xenografts in mice. “How many more negative data do you want? It’s very depressing.”
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Breakaway from Cancer is an integral, complementary component of the Amgen Tour of California, and it benefits cancer patients across the country. Amgen was proud to host the Breakaway from Cancer charity ride in our headquarters city and join members of the community to raise additional funds to help empower people with cancer so they can live well with the disease.
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We need to get cancer patients near treatment and keep them near their families at the same time. These three mobile homes are only the beginning. With the help of others in the mobile home and transportation industries, we hope to make a significant impact on the lives of people with cancer in the Gulf Region.
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This operation suggests that drugs ordered from so-called 'Canadian' Internet sites are not drugs of known safety and efficacy. These results make clear there are Internet sites that claim to be 'Canadian' that, in fact, are peddling drugs of dubious origin, safety, and efficacy. We believe that these 'bait and switch' tactics --- offering patients one thing and then giving them something else -- are misleading to patients and potentially harmful to the public health.
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The doctor should be opaque to his patients and, like a mirror, should show them nothing but what is shown to him.
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My own medical perspective is that animal cancer research should be regarded as the scientific equivalent of gossip – with about the same chance of turning out to be true, i.e. truly effective in humans. Some gossip turns out to be true, but most of it does not…and gossip can cause great anguish for those affected, in this case millions of desperate cancer patients worldwide.
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One of the most appalling comments on our present way of life is that half of all the beds in our hospitals are reserved for patients with nervous and mental troubles, patients who have collapsed under the crushing burden of accumulated yesterdays and fearful tomorrows. Yet a vast majority of those people would be walking the streets today, leading happy, useful lives, if they had only heeded the words of Jesus: 'Have no anxiety about the morrow'; or the words of Sir William Osler; 'Live in day-tight compartments.
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Towns are full of people, houses full of tenants, hotels full of guests, trains full of travelers, caf?s full of customers, parks full of promenaders, consulting-rooms of famous doctors full of patients, theatres full of spectators, and beaches full of bathers. What previously was, in general, no problem, now begins to be an everyday one, namely, to find room.
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Animal research was NOT responsible for the development of coronary bypass surgery. In 1961 in France, Kunlin first used a portion of a person's own vein to replace obstructed arterial segments. This gave birth to arterial bypass surgery for different parts of the body, the heart included. By contrast, Beck of Ohio and Vineburg of Canada took their theories to the animal laboratory in search of surgical answer to the complications of coronary artery disease. Each devised more than one procedure, envisioning success from their findings in animals. Not long after, their recommended operations were performed on thousands of human patients. What were the results? To say the least, unworthy. To put it bluntly; a fiasco, a total failure. I am witness to this event and the least I can do is speak out. Animal experimentation inevitably leads to human experimentation. That is the final verdict, sad as it is. And the toll mounts on both sides.'
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One of the fundamental reasons why so many doctors become cynical and disillusioned is precisely because, when the abstract idealism has worn thin, they are uncertain about the value of the actual lives of the patients they are treating. This is not because they are callous or personally inhuman: it is because they live in and accept a society which is incapable of knowing what a human life is worth.
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If architects want to strengthen a decrepit arch, they increase the load that is laid upon it, for thereby the parts are joined more firmly together. So, if therapists wish to foster their patients' mental health, they should not be afraid to increase that load through a reorientation toward the meaning of one's life.
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The analytic psychotherapist thus has a threefold battle to wage -- in his own mind against the forces which seek to drag him down from the analytic level; outside the analysis, against opponents who dispute the importance he attaches to the sexual instinctual forces and hinder him from making use of them in his scientific technique; and inside the analysis, against his patients, who at first behave like opponents but later on reveal the overvaluation of sexual life which dominates them, and who try to make him captive to their socially untamed passion.
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We achieve active mastery over illness and death by delegating all responsibility for their management to physicians, and by exiling the sick and the dying to hospitals. But hospitals serve the convenience of staff not patients: we cannot be properly ill in a hospital, nor die in one decently; we can do so only among those who love and value us. The result is the institutionalized dehumanization of the ill, characteristic of our age.
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Aided and abetted by corrupt analysts, patients who have nothing better to do with their lives often use the psychoanalytic situation to transform insignificant childhood hurts into private shrines at which they worship unceasingly the enormity of the offenses committed against them. This solution is immensely flattering to the patients -- as are all forms of unmerited self-aggrandizement; it is immensely profitable for the analysts -- as are all forms pandering to people's vanity; and it is often immensely unpleasant for nearly everyone else in the patient's life.
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The very fact that companion animals are so highly regarded raises difficult issues for agricultural and performance animal doctors. Some of these animals are not markedly different in their mental capacities from many companion animals. At a time the profession seeks to promote companion animals as members of the family, to what extent must it also advocate the interests of its food, farm, and performance animal patients?. . . Nevertheless, discussions devoid of attention to animal interests are appearing with frequency in the literature espousing the model of the veterinarian as herd health consultant.
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I was surprised that we did as well as we did. Per capita spending for mental health has been going down for more than a decade. When per capita spending goes down, patients' access to mental health services suffers.
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I had always worked with the temperamental conviction that at bottom there are no insoluble problems, and experience justified me in so far as I have often seen patients simply outgrow a problem that had destroyed others. This 'outgrowing,' as I formerly called it, proved on further investigation to be a new level of consciousness. Some higher or wider interest appeared on the patient's horizon, and through this broadening of his outlook the insoluble problem lost its urgency.
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We stuck in all the symptoms that diabetics get, ranging from serious things like death to less serious things like ballooning of the arteries in the legs. While it didn't meet the goal at the combination endpoint, it did on the one that really matters to patients: death, heart attacks and strokes.
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'As for bypass surgery, animal research actually retarded this therapy for humans. Because a dog's clotting characteristics and coronary valves are so different from ours, the initial human patients died. The first success was Dr Kunlin's work in France. Dr Kunlin's work was clinical and had nothing to do with animal research.'---
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It’s been well known for maybe two decades that many of these preclinical human cancer models have very little predictive power in terms of how actual human beings – actual human tumours inside patients – will respond…Preclinical models of human cancer, in large part, stink…Hundreds of millions of dollars are being wasted every year by drug companies using these [animal] models…
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Doctors are not servants of their patients, they are traders like everyone else in a free society and they should bear that title proudly considering the crucial importance of the services they offer.
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Cancer patients are lied to, not just because the disease is (or is thought to be) a death sentence, but because it is felt to be obscene -- in the original meaning of that word: ill-omened, abominable, repugnant to the senses.
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Our study provides beginning evidence for the important role art therapy can play in reducing symptoms. Art therapy provides a distraction that allows patients to focus on something positive instead of their health for a time, and it also gives patients something they can control.
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To study the phenomenon of disease without books is to sail an uncharted sea, while to study books without patients is not to go to sea at all.
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The headline reads, 'Docs say patients make them prescribe useless antibiotics.' This puts a physician in roughly the same predicament as a serial killer. The latter says, 'Stop me before I kill again, while the former says, 'Stop me before I prescribe again.'
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In a hospital, half of the patients get better food than at home.
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The doctor of the future will give no medicine, but will educate his patients in the care of the human frame, in diet, and in the cause and prevention of disease.
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In essence, the D.C. District Court of Appeals said the rights of terminally ill cancer patients must be protected and not dismissed lightly -- and we completely agree.
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It is believed by experienced doctors that the heat which oozes out of the hand, on being applied to the sick, is highly salutary. It has often appeared, while I have been soothing my patients, as if there was a singular property in my hands to pull and draw away from the affected parts aches and diverse impurities, by laying my hand upon the place, and extending my fingers toward it. Thus it is known to some of the learned that health may be implanted in the sick by certain gestures, and by contact, as some diseases may be communicated from one to another.
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I was once thrown out of a mental hospital for depressing the other patients.
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