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Extrapolated Quotations

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After massive blood loss a dog's intestines are congested, while in humans we see pallor and ischemia. No wonder conclusions from dog experiments extrapolated to human beings frequently brings about catastrophic results and regrettable failures, which occurred with the earlier models of heart valves and in the first several years of using the heart-lung machine. For the benefit of medical science vivisection should be stopped. We must put an end to the medical fraud of vivisection.'

+Fav | Go to Quote / Comment | Dr Moneim A Fadali |

The principal method of determining potential carcinogenicity of substances is based on studies of daily administration of huge doses of chemicals to inbred rodents for a lifetime. Then by questionable models, which include large safety factors, the results are extrapolated to effects of minuscule doses in humans... The rodent MTD test that labels plant chemicals as cancer-causing in humans is misleading. The test is likewise of limited value for synthetic chemicals. The standard carcinogen tests that use rodents are an obsolescent relic of the ignorance of past decades.

+Fav | Go to Quote / Comment | Philip H Abelson |