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Carcinogenesis Quotations

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The lifetime feeding study of mice and rats appears to have less than a 50% probability of finding known human carcinogens. On the basis of probability theory, we would have been better off to toss a coin...The `definitive bioassay for carcinogenesis' as now designed has never been subjected to proper validation as an assay for human carcinogens. At attempt made in this paper to examine the literature suggests that it may have an unacceptably high false negative rate and that it produces so many contradictory answers as to suggest a very poor specificity.

+Fav | Go to Quote / Comment | Dr David Salsburg |

It is painfully clear that carcinogenesis in the mouse cannot now be predicted from positive data obtained from the rat and vice versa.

+Fav | Go to Quote / Comment | Dr F J Di Carlo |