Change is needed. Thirty years of experience with subcutaneous xenografts, human tumors implanted under the skin of the mouse, have satisfied few because so many drugs that cure cancer in these mice fail to help humans. A 2004 analysis in the Journal of the American Medical Association showed that only 3.8% of patients in phase I cancer drug trials between 1991 and 2002 achieved an objective clinical response — and the response rate is declining. Almost all drugs tried in humans work against subcutaneous xenografts in mice. “How many more negative data do you want? It’s very depressing.”

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[Many of these thoughtless, stupid remarks are uttered by sports figures, but not all. In 2002 Sen. Trent Lott, R-Miss., said the United States could have avoided what he called] all these problems, ... All the laws of Washington and all the bayonets of the Army cannot force the Negro into our homes, our schools, our churches.

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Technology has done well, not necessarily because of the crash, but because it has moved up the alert that the market's concentrating on a 2002 recovery. Rather than focusing on the earnings that are going to come out in the fourth quarter, people are looking forward rather than near-term.

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Kenya is an example to the rest of the region of what could be accomplished with elections that allow people to make a choice as to how they will be governed, ... We look forward to the election that will be taking place in 2002 for the people of Kenya to once again come forward and express their desires with respect to how they will be governed.

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Touching the Future

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