The timid and fearful first failures dismay, but the stout heart stays trying by night and by day. He values his failures as lessons that teach The one way to get to the goal he would reach.
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The fundamental problem in drug discovery for cancer is that the model systems are not predictive at all. ancer research at Merck Research Laboratories in West Point, Pennsylvania…Researchers blamed the failures on the fact that the drugs were being tested against mouse, not human, tumors… the xenograft tumors don't behave like naturally occurring tumors in humans – they don't spread to other tissues, for example. Thus, drugs tested in the xenografts appeared effective but worked poorly in humans.
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My experiences of men has neither disposed me to think worse of them nor be indisposed to serve them: nor, in spite of failures which I lament, of errors which I now see and acknowledge, or the present aspect of affairs, do I despair of the future. The truth is this: The march of Providence is so slow and our desires so impatient; the work of progress so immense and our means of aiding it so feeble; the life of humanity is so long, that of the individual so brief, that we often see only the ebb of the advancing wave and are thus discouraged. It is history that teaches us to hope.
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I am often confronted by the necessity of standing by one of my empirical selves and relinquishing the rest. Not that I would not. If I could, be... a great athlete and make a million a year, be a wit, a born -- vivant and a lady killer, as well as a philosopher, a philanthropist ... and saint. But the thing is simply impossible. The millionaire's work would run counter to the saint s; the bon-vivant and the philanthropist would trip each other up; the philosopher and the lady killer could not well keep house in the same tenement of clay. Such different characters may conceivably, at the outset of life. Be alike possible for a man. But to make any one of them actual, the rest must more of less be suppressed. So the seeker of his truest, strongest, deepest self must review the list carefully and pick out on which to stake his salvation. All other selves thereupon become unreal, but the fortunes of this self are real. Its failure are real failures, its triumphs real triumphs carrying shame and gladness with them.
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When we can begin to take our failures seriously, it means we are ceasing to be afraid of them. It is of immense importance to learn to laugh at ourselves.
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My Declaration of Self Esteem
I am Me. In all the world, there is no one else exactly like me. Everything that comes out of me is authentically mine, because I alone chose it -- I own everything about me: my body, my feelings, my mouth, my voice, all my actions, whether they be to others or myself. I own my fantasies, my dreams, my hopes, my fears. I own my triumphs and successes, all my failures and mistakes. Because I own all of me, I can become intimately acquainted with me. By so doing, I can love me and be friendly with all my parts. I know there are aspects about myself that puzzle me, and other aspects that I do not know -- but as long as I am friendly and loving to myself, I can courageously and hopefully look for solutions to the puzzles and ways to find out more about me. However I look and sound, whatever I say and do, and whatever I think and feel at a given moment in time is authentically me. If later some parts of how I looked, sounded, thought, and felt turn out to be unfitting, I can discard that which is unfitting, keep the rest, and invent something new for that which I discarded. I can see, hear, feel, think, say, and do. I have the tools to survive, to be close to others, to be productive, and to make sense and order out of the world of people and things outside of me. I own me, and therefore, I can engineer me. I am me, and I am Okay.
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It does not matter how many tumbles you have in this life, so long as you do not get dirty when you tumble; it is only the people who have to stop to be washed and made clean, who must necessarily lose the race. And I can assure you that there is the greatest practical benefit in making a few failures early in life. You learn that which is of inestimable importance
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After massive blood loss a dog's intestines are congested, while in humans we see pallor and ischemia. No wonder conclusions from dog experiments extrapolated to human beings frequently brings about catastrophic results and regrettable failures, which occurred with the earlier models of heart valves and in the first several years of using the heart-lung machine. For the benefit of medical science vivisection should be stopped. We must put an end to the medical fraud of vivisection.'
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Opportunities abound, not just to avoid making mistakes in the marketplace - which animals pay for with their lives - but to say and do even small things that will make a huge difference in how animals are treated and viewed. Act on the adage, 'All that evil needs to triumph is for enough good people to do nothing.' Wherever you are, if you see something wrong, put yourself in the animal's place and speak up! There are always other people who hold the same view but are waiting for someone else to go first. That someone is you. Even the terminally shy can be shameless salespeople, planting animal rights seeds in others' minds without even speaking to them! In restaurants talk loudly to your companion about how the vegetarian food is the best! On crowded elevators, discuss how 'Sarah' lost 30 pounds since she stopped eating chicken and fish! There is no 'one true way' to animal liberation - all that matters is that you are doing something. Don't fret over failures! REMEMBER: Every single act brings animal liberation that much closer!
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I will act now. I will act now. I will act now. Henceforth, I will repeat these words each hour, each day, everyday, until the words become as much a habit as my breathing, and the action which follows becomes as instinctive as the blinking of my eyelids. With these words I can condition my mind to perform every action necessary for my success. I will act now. I will repeat these words again and again and again. I will walk where failures fear to walk. I will work when failures seek rest. I will act now for now is all I have. Tomorrow is the day reserved for the labor of the lazy. I am not lazy. Tomorrow is the day when the failure will succeed. I am not a failure. I will act now. Success will not wait. If I delay, success will become wed to another and lost to me forever. This is the time. This is the place. I am the person.
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We climb to heaven most often on the ruins of our cherished plans, finding our failures were successes.
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I believe the single most significant decision I can make on a day-to-day basis is my choice of attitude. It is more important than my past, my education, my bankroll, my successes or failures, fame or pain, what other people think of me or say about me, my circumstances, or my position. Attitude keeps me going or cripples my progress. It alone fuels my fire or assaults my hope. When my attitudes are right, there is no barrier too high, no valley too deep, no dream too extreme, no challenge too great for me.
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Total self-esteem requires total and unconditional acceptance of yourself. You are a unique and worthy individual, regardless of your mistakes, defeats and failures, despite what others may think, say or feel about you or your behavior. If you truly accept and love yourself, you won't have a driving need for attention and approval. Self-esteem is a genuine love of self. Stop all adverse value judging of yourself. Stop accepting the adverse value judgments of others. Purge yourself of all condemnation, shame, blame, guilt & remorse.
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Failures are finger posts on the road to achievement.
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In order to form correct habits, we should seek the company of persons of sound moral and religious influence. We should constantly bear in mind that we may be fitting to inhabit the heavenly courts. The precious hours of probation are granted that we may remove every defect from the character; and we should seek to do this, not only that we may obtain the future life, but that we may be useful here. Young men and women should regard a good character as a capital of more value than gold or silver or stocks. It will be unaffected by panics and failures, and will bring rich returns when earthly possessions shall be swept away.
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We have scarcely gotten home ... when our children's sneezes greet us, skinned knees bleed after waiting all day to do so. There is the bellyache and the burned-out basement bulb, the stalled car and the incontinent cat. The windows frost, the toilets sweat, the body of our spouse is one cold shoulder and the darkness of our bedroom is soon full of the fallen shadows of our failures.
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To have a commission appointed exclusively by President Bush investigate his administration's intelligence failures in Iraq does not inspire confidence in its independence,
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Our achievements speak for themselves. What we have to keep track of are our failures, discouragements and doubts. We tend to forget the past difficulties, the many false starts, and the painful groping. We see our past achievements as the end results of a clean forward thrust, and our present difficulties as signs of decline and decay.
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Of course, our failures are a consequence of many factors, but possibly one of the most important is the fact that society operates on the theory that specialization is the key to success, not realizing that specialization precludes comprehensive thinking.
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Bank failures are caused by depositors who don't deposit enough money to cover losses due to mismanagement.
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Once you agree upon the price you and your family must pay for success, it enables you to ignore the minor hurts, the opponent's pressure, and the temporary failures.
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A university is not a service station. Neither is it a political society, nor a meeting place for political societies. With all its limitations and failures, and they are invariably many, it is the best and most benign side of our society insofar as that society aims to cherish the human mind.
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The failures of the press have contributed immensely to the emergence of a talk-show nation, in which public discourse is reduced to ranting and raving and posturing.
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The economic miracle that has been the United States was not produced by socialized enterprises, by government-union-industry cartels or by centralized economic planning. It was produced by private enterprises in a profit-and-loss system. And losses were at least as important in weeding out failures as profits in fostering successes. Let government succor failures, and we shall be headed for stagnation and decline.
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The awareness of the ambiguity of one's highest achievements (as well as one's deepest failures) is a definite symptom of maturity.
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The brotherhood of men does not imply their equality. Families have their fools and their men of genius, their black sheep and their saints, their worldly successes and their worldly failures. A man should treat his brothers lovingly and with justice, according to the deserts of each. But the deserts of every brother are not the same.
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An inventor fails 999 times, and if he succeeds once, he's in. He treats his failures simply as practice shots.
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Nothing can be called failure until you accept it as such. You can transmute all past failures and mistakes into assets. Adversity is Nature's method of disciplining people to learn to take possession of their own minds. Greatest blessings often come from the greatest adversities. Study yourself carefully and you may discover that your own emotions are your greatest handicap in the business of accurate thinking.
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Do not brood over your past mistakes and failures as this will only fill your mind with grief, regret and depression. Do not repeat them in the future.
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It is a mistake to suppose that men succeed through success; they much oftener succeed through failures. Precept, study, advice, and example could never have taught them so well as failure has done.
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