He who would pass his declining years with honor and comfort, should, when young, consider that he may one day become old, and remember when he is old, that he has once been young.
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Change is needed. Thirty years of experience with subcutaneous xenografts, human tumors implanted under the skin of the mouse, have satisfied few because so many drugs that cure cancer in these mice fail to help humans. A 2004 analysis in the Journal of the American Medical Association showed that only 3.8% of patients in phase I cancer drug trials between 1991 and 2002 achieved an objective clinical response — and the response rate is declining. Almost all drugs tried in humans work against subcutaneous xenografts in mice. “How many more negative data do you want? It’s very depressing.”
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We are declining in science ... in the 5th and 6th grades. Young ladies are not entering math and science -- and when they do, they go to medicine.
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There is timing in the whole life of the warrior, in his thriving and declining, in his harmony and discord. Similarly, there is timing in the Way of the merchant, in the rise and fall of capital. All things entail rising and falling timing. You must be able to discern this.
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I am reminded of the professor who, in his declining hours, was asked by his devoted pupils for his final counsel. He replied, 'Verify your quotations.'
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As for old age, embrace and love it. It abounds with pleasure if you know how to use it. The gradually declining years are among the sweetest in a man's life, and I maintain that, even when they have reached the extreme limit, they have their pleasure still.
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Where can we find two better hemispheres/ Without sharp North, without declining West?
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Because it often happens that an old family, with traditions that are entirely practical, sober and bourgeois, undergoes in its declining days...
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[In the face of declining poll numbers for the president in the wake of the Katrina disaster and a growing dissatisfaction with the general direction of the country, the DeLay indictment put already defensive Republicans, who control the entire government, further back on their heels.] [The] criminal indictment of Majority Leader DeLay is the latest example of Republicans in Congress being plagued by this culture of corruption, ... This all extends to the White House as well.
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Avarice is the vice of declining years.
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Newspaper readership is declining like crazy. In fact, there's a good chance that nobody is reading my column.
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