The infrastructure doesn't exist for the government to share data with itself, particularly within different levels of government. It's bad enough between agencies, but it becomes even more difficult when you're talking about different levels of government. Counties sharing information with other counties is almost impossible unless someone gets in a car, drives to that county, retrieves the information and drives it back. What the private sector does very well is build the infrastructure which allows that information, which is public, to flow freely across jurisdictional and geographical lines. That's the benefit that the private sector has brought to this process.
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I was raised on a dairy farm and ate plenty of meat and eggs until about twenty years ago. I started doing nutritional research, and a decade or so after that my family made some major dietary changes. I'm just paying attention to what the data are telling me. The scientific evidence came first.
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So far, all of the ethical discussions about sex selection have focused on 'what if' scenarios without any legitimate data. This study should provide a legitimate framework to better lead the discussion about the realistic implications of sex selection technology.
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The decrease in pervasive attacks in 2005 is counter-intuitive to what society at large believes is a major threat to their personal data. IBM believes that the environment has shifted - with increased security protection on most systems and stiffer penalties, we are seeing organized, committed, and tenacious profiteers enter this space. This means that attacks will be more targeted and potentially damaging. Organizations around the world - from the public and private sectors - must move quickly and work together to address this growing challenge.
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Change is needed. Thirty years of experience with subcutaneous xenografts, human tumors implanted under the skin of the mouse, have satisfied few because so many drugs that cure cancer in these mice fail to help humans. A 2004 analysis in the Journal of the American Medical Association showed that only 3.8% of patients in phase I cancer drug trials between 1991 and 2002 achieved an objective clinical response — and the response rate is declining. Almost all drugs tried in humans work against subcutaneous xenografts in mice. “How many more negative data do you want? It’s very depressing.”
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Since its inception 25 years ago, EPA [the US Environmental Protection Agency] has applied the same logic to hundreds of other substances, extrapolating from high levels in animal studies to arrive at acceptable levels for humans. But that approach, say scientists both inside and outside the federal government, may no longer be the best way to safeguard public health...EPA's new emphasis on molecular data is based on a growing body of evidence that extrapolations from megadoses can provide a misleading picture of the effects of low-level exposure. Chloroform is a good example. EPA's current strict standards were derived from a study in which mice developed liver tumors after exposure to massive daily doses of chloroform pumped into their stomachs over several months. However, those findings may not be relevant to human exposures, according to a paper picked by the Society of Toxicology as the best published last year in its journal.
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Reach me down my Tycho Brahe, I would know him when we meet, When I share my later science, sitting humbly at his feet; He may know the law of all things, yet be ignorant of how We are working to completion, working on from then to now. Pray remember that I leave you all my theory complete, Lacking only certain data for your adding, as is meet, And remember men will scorn it, 'tis original and true, And the obliquy of newness may fall bitterly on you. But, my pupil, as my pupil you have learned the worth of scorn, You have laughed with me at pity, we have joyed to be forlorn, What for us are all distractions of men's fellowship and smiles; What for us the Goddess Pleasure with her meretricious smiles. You may tell that German College that their honor comes too late, But they must not waste repentance on the grizzly savant's fate. Though my soul may set in darkness, it will rise in perfect light; I have loved the stars too fondly to be fearful of the night.
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Yes, I think it is very clear to all of us who are engaged in the business of assessing toxicity data that, when volumes of data are proudly presented to us after a carcinogenicity study, showing that there was a tumour in this organ or that, we look at it and we scratch our heads, and we wonder what on earth we can make of it. This is especially true when huge doses are given, with nothing to suggest what would be expected at low doses. I think very often the carcinogenicity studies are a waste of everybody's time and a fearful waste of animals. They are conducted partly because we are not sure what to do instead, and partly because they are a political gesture and a very miserable one at that.
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It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories, instead of theories to suit facts.
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The intelligence to know what the attributes of the device are in terms of its output characteristics, and then do the transformation of [data] from a potentially more robust source [to a format] the device can understand -- that would be a major service.
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The larger research programs that the National Science Foundation and National Institutes of Health are sponsoring require a machine like this to manage such large amounts of data.
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The main value of threat response services is the global intelligence network that feeds it. A robust global network with sophisticated data analysis differentiates one service from the next. It is a key determining factor when choosing a security provider.
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For 39 agents with both xenograft data and Phase II clinical trials results available, in vivo activity in a particular histology in a tumour model did not closely correlate with activity in the same human cancer histology, casting doubt on the correspondence of the pre-clinical models to clinical results.
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The constant dilemma of the information age is that our ability to gathera sea of data greatly exceeds the tools and techniques available to sort,extract, and apply the information we've collected.
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Debugging tips from the Master, Sherlock Holmes:
'It is a capital mistake to theorize before one has data. Insensibly one begins to twist facts to suit theories instead of theories to suit facts.'
'As a rule, the more bizarre a thing is, the less mysterious it proves to be.'
'Perhaps I have trained myself to see what others overlook.'
'There is nothing more deceptive than an obvious fact.'
'Chance has put in our way a most singular and whimsical problem, and its solution is its own reward.'
'I am glad of all details, whether they seem to you to be relevant or not.'
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The U.S has acquired reservoirs of goodwill around the globe over many years. But it is clear - from polling data and ample anecdotal evidence - that America is losing its allure in much of the world.
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Cyberspace. A consensual hallucination experienced daily by billions of legitimate operators, in every nation, by children being taught mathematical concepts... A graphic representation of data abstracted from the banks of every computer in the human system. Unthinkable complexity. Lines of light ranged in the nonspace of the mind, clusters and constellations of data. Like city lights, receding...
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Data is not information, Information is not knowledge, Knowledge is not understanding, Understanding is not wisdom.
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The intellectual equipment needed for the job of the future is an ability to define problems, quickly assimilate relevant data, conceptualize and reorganize the information, make deductive and inductive leaps with it, ask hard questions about it, discuss findings with colleagues, work collaboratively to find solutions and then convince others.
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Soft data, hard conflicts.
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These data indicate energy sector volatility is not generally affecting prices elsewhere in the economy. Surging productivity growth has permitted most producers to absorb higher energy costs and still enjoy strong profits growth.
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By the data to date, there is only one animal in the Galaxy dangerous to man-man himself. So he must supply his own indispensable competition. He has no enemy to help him.
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Computer hacking and data theft are serious crimes in our modern economy. Because of the volume and value of the data stolen by (Levine), this quickly became a priority case for us.
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These data provide strong evidence for a substantial protective effect of cruciferous vegetables on lung cancer.
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This antenna allows you to track the satellites to bring the signal onto the airplane, but the real technology breakthrough has been using that same technology to bring the broadband data off the airplane.
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Data from dose-response relationships are sometimes employed to estimate the expected tumour incidence at dose levels very much lower than those which could possibly be employed in conventional [animal] experiments. A number of mathematical models have been employed in such estimates and the results obtained vary considerably. Despite these uncertainties - and the possibly greater ones in extrapolating from animals to man - such models are often employed in some quarters to estimate the likely risk to man.
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The EIA data indicate there's a lot of crude out there,
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Experts often possess more data than judgment.
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Wierd Error Messages:
HAPPY BIRTHDAY! (sole response from a malfunctioning motherboard)
I DON'T EAT RASINS. (From a Data General AOS/VS System)
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Science begins with the world we have to live in, accepting its data and trying to explain its laws. From there, it moves toward the imaginati...
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