In Tamoxifen’s case, a drug first developed as a potential contraceptive languished for many years before its present application was found. Furthermore, its propensity to cause liver tumours in rats, a toxicity problem that thankfully does not carry over into humans, was not detected until after the drug had been on the market for many years. If it had been found in preclinical testing, the drug would almost certainly have been withdrawn from the pipeline.
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If a square peg doesnt fit a round hole, neither the peg nor the hole is to blame. Between two people, the question whose fault is it? is the friend of argumentation and the destroyer of growth-oriented communication. Assigning blame involves listening to criticize and responding to defend, speaking to lower the other person rather than speaking to build each up. Relational progress is impossible as long as blame is the focus because blame and progress are enemies. In our litigation-hungry society we must take care that focusing on fault - which is proper for the courtroom - doesnt carry over into interpersonal relationships. The heart of loving communication is listening to understand.
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For cowards the road of desertion should be left open; they will carry over to the enemy nothing, but their fears.
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Warning is given not to carry over, without reservation, to man, the conclusions based on animal experiments. In monkeys none of the powerful carcinogens [of man] has been shown to produce cancers.
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