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Irritate

Definition

[v] excite to an abnormal condition, of chafe or inflame; "Aspirin irritates my stomach"
[v] physiology and biology: excite to some characteristic action or condition, as motion, contraction, or nervous impulse, by the application of a stimulus; "irritate the glands of a leaf"
[v] cause annoyance in; disturb, esp. by minor irritations; "Mosquitoes buzzing in my ear really bothers me"; "It irritates me that she never closes the door after she leaves"

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Antonyms

soothe