Humor is my mechanism for dealing with the hard reality of the world.
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A chronic lack of pleasure, of any enjoyable, rewarding or stimulating experiences, produces a slow, gradual, day-by-day erosion of man's emotional vitality, which he may ignore or repress, but which is recorded by the relentless computer of his subconscious mechanism that registers an ebbing flow, then a trickle, then a few last drops of fuel--until the day when his inner motor stops and he wonders desperately why he has no desire to go on, unable to find any definable cause of his hopeless, chronic sense of exhaustion.
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1-3 Butadiene, an important industrial chemical and a common environmental air pollutant, has been shown to be a weak carcinogen in the rat, but a potent carcinogen in the B6C3F1 mouse. This species difference makes risk extrapolation to humans difficult, and the underlying mechanism must be clarified before meaningful risk extrapolation to humans can be made.
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Bureaucracy is a giant mechanism operated by pygmies.
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Extrapolating from one species to another is fraught with uncertainty... For almost all of- the chemicals tested to date, rodent bio-assays have not been cost-effective. They give limited and uncertain information on carcinogenicity, generally give no indication of mechanism of action, and require years to complete.' [They are] 'rarely the best approach for deciding whether to classify a chemical as a human carcinogen.
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Dogs have been extensively used in heart research, but their coronary arteries differ from those of humans - they have smaller connections with one another and the left coronary artery dominates, while in humans the right does so. In addition, the conduction system has a different pattern of blood supply, and consequently, researchers have had difficulty in producing ischemic heart blocks in dogs, which occurs frequently in humans. The blood coagulation mechanism is unlike ours, therefore using dogs to test prosthetic devices and valves is unreliable. A dog's reaction to shock is also very different to that of humans.
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... numerous chemicals have been found to have potential toxicity/carcinogenicity in rat or mouse, which, we are reasonably certain, have little or no potential hazard in man. The reason for this is again species differences, for the biological defence mechanism which protects against toxic chemicals is most highly evolved in man, who therefore generally has a higher resistance to chemical toxicity and carcinogenicity than have rodents and other species.
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I strongly urge the voters of Colorado to reject Referendum C, or any action that would suspend Colorado's Taxpayers Bill of Rights. I strongly favor the continued and uninterrupted use of TABOR, including it's so called ratchet mechanism. The ratchet is one of the best features of TABOR. It is the only thing that will reduce out-of-control government spending.
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It is amusing to discover, in the twentieth century, that the quarrels between two lovers, two mathematicians, two nations, two economic systems, usually assumed insoluble in a finite period should exhibit one mechanism, the semantic mechanism of identification -- the discovery of which makes universal agreement possible, in mathematics and in life.
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The law isn't justice. It's a very imperfect mechanism. If you press exactly the right buttons and are also lucky, justice may show up in the answer. A mechanism is all the law was ever intended to be.
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The secretary-general sees the fund as an innovative and flexible mechanism for advancing the UN democracy agenda. The fund will support projects aimed at consolidating and strengthening democratic institutions and processes, such as the drafting of constitutions and the development of pluralistic media.
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The most powerful force possessed by the individual citizen is her own government. ... Government is the only organized mechanism that makes possible that level of shared disinterest known as the public good.
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You must listen to the protesters who are going to Seattle to express frustration about a system they believe excludes them. Citizens should have a voice not only in the decisions of their own governments, but also in those of international bodies. They must have access to information and be confident a mechanism exists to address legitimate concerns. China will find in America a confident and willing trade partner.
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No one is going to turn down a good meal because he does not understand the digestive mechanism.
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Everyone has a success mechanism and a failure mechanism. The failure mechanism goes off by itself. The success mechanism only goes off with a goal. Every time we write down and talk about a goal we push the button to start the success mechanism.
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The concept of progress acts as a protective mechanism to shield us from the terrors of the future.
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The mechanism that directs government cannot be virtuous, because it is impossible to thwart every crime, to protect oneself from every criminal without being criminal too; that which directs corrupt mankind must be corrupt itself; and it will never be by means of virtue, virtue being inert and passive, that you will maintain control over vice, which is ever active: the governor must be more energetic than the governed.
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For man is not the creature and product of Mechanism; but, in a far truer sense, its creator and producer.
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Thus man of all creatures is more than a creature, he is also a creator. Man alone can direct his success mechanism by the use of imagination, or imaging ability.
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One of the problems of taking things apart and seeing how they work - supposing you're trying to find out how a cat works--you take that cat apart to see how it works, what you've got in your hands is a non-working cat. The cat wasn't a sort of clunky mechanism that was susceptible to our available tools of analysis.
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Science is a mechanism, a way of trying to improve your knowledge of nature. It's a system for testing your thoughts against the universe, and seeing whether they match.
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Battles, in these ages, are transacted by mechanism; with the slightest possible development of human individuality or spontaneity; men now even die, and kill one another, in an artificial manner.
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