Dogs have been extensively used in heart research, but their coronary arteries differ from those of humans - they have smaller connections with one another and the left coronary artery dominates, while in humans the right does so. In addition, the conduction system has a different pattern of blood supply, and consequently, researchers have had difficulty in producing ischemic heart blocks in dogs, which occurs frequently in humans. The blood coagulation mechanism is unlike ours, therefore using dogs to test prosthetic devices and valves is unreliable. A dog's reaction to shock is also very different to that of humans.
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I'm struck by the insidious, computer-driven tendency to take things out of the domain of muscular activity and put them into the domain of mental activity. The transfer is not paying off. Sure, muscles are unreliable, but they represent several million years of accumulated finesse.
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According to Dr Ray Greek: 'Most pharmaceutical firms do more testing than the government requires, so they can say in court that they saw no effects like the one that killed the plaintiff's wife. Officials will tell you off the record that they rely on animal testing and think that it is a big factor in protection from lawsuits.' Or, the companies can turn around and dismiss the animal tests as being unreliable in humans. Either way, it is extremely hard for victims to take legal action against them.
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Money is a singular thing. It ranks with love as man's greatest source of joy. And with death as his greatest source of anxiety. Over all history it has oppressed nearly all people in one of two ways: either it has been abundant and very unreliable, or reliable and very scarce.
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Gain a modest reputation for being unreliable and you will never be asked to do a thing.
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Nothing is more unreliable than the populace, nothing more obscure than human intentions, nothing more deceptive than the whole electoral syst...
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Nothing is more unreliable than the populace, nothing more obscure than human intentions, nothing more deceptive than the whole electoral system.
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Don't be misled by History, or any other unreliable source.
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