When I Grow Up When I grow up, I wonder if people will be more afraid to cry than they are to die. Will I be able to see a rainbow in a small-filled sky. Will there be any trees left, if not how will the planet survive. Will there be a website at www.lifeairsupply.com. When I grow up, if I got bored and had nothing to do and me and my son built a canoe and water that was once blue would be so poluted it would give us the flu. Will a thousand dollars be enough for a shoe. Will I have to be like you, letting money make the decision for everything that I do. When I grow up, will the existance of dolphins and whales just be a story I tell, starting with Once upon a time and ending with where did we fail. Will adults be the hammer and nail. Will schools be next door to jails. Will the truth be illegal for sale. When I grow up, will people be on the news for anything besides killing. Will those drug dealers still be outside of my building. Will they ever learn how to love or are they still afraid of the feeling. Will tv and music videos still raise America's children. Will students go home from school in a bullet proof bus. What if children had no one to trust, that would hurt me so much and i just want to be happy, when i grow up.
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In the 1940s a survey listed the top seven discipline problems in public schools talking, chewing gum, making noise, running in the halls, getting out of turn in line, wearing improper clothes, not putting paper in wastebaskets. A 1980s survey lists these top seven drug abuse, alcohol abuse, pregnancy, suicide, rape, robbery, assault. (Arson, gang warfare and venereal disease are also-rans.)
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Earnings growth has been surprisingly low for drug stocks and there is more of that to come as we go through a cycle of patent expirations. But I think the stocks are close to being washed out and if you have patience they will do quite well over a longer period of time.
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Laugh at yourself and at life. Not in the spirit of derision or whining self-pity, but as a remedy, a miracle drug, that will ease your pain, cure your depression, and help you to put in perspective that seemingly terrible defeat and worry with laughter at your predicaments, thus freeing your mind to think clearly toward the solution that is certain to come. Never take yourself too seriously.
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If an addict who has been completely cured starts smoking again he no longer experiences the discomfort of his first addiction. There exists, therefore, outside alkaloids and habit, a sense for opium, an intangible habit which lives on, despite the recasting of the organism. The dead drug leaves a ghost behind. At certain hours it haunts the house.
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To me, the irony of this involvement with size, as I observed earlier, is the unwillingness or inability of so many Americans to identify themselves with something as vast as the United States. Bigger cars, bigger parking lots, bigger corporate structures, bigger farms, bigger drug stores, bigger supermarkets, bigger motion-picture screens. The tangible and the functional expand, while the intangible and the beautiful shrink. Left to wither is the national purpose, national educational needs, literature and theater, and our critical faculties. The national dialogue is gradually being lost in a froth of misleading self-congratulation and cliche. National needs and interests are slowly being submerged by the national preoccupation with the irrelevant.
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If we could sniff or swallow something that would, for five or six hours each day, abolish our solitude as individuals, atone us with our fellows in a glowing exaltation of affection and make life in all its aspects seem not only worth living, but divinely beautiful and significant, and if this heavenly, world-transfiguring drug were of such a kind that we could wake up next morning with a clear head and an undamaged constitution -- then, it seems to me, all our problems (and not merely the one small problem of discovering a novel pleasure) would be wholly solved and earth would become paradise.
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Animal model systems in cancer research have been a total failure…not a single essential drug for the treatment of human cancer was first picked up by an animal model system. All of the drugs in wide current clinical use were only put into animal model systems after finding clinical clues to their therapeutic possibility. The money was spent…for two main reasons. First, it was a highly profitable undertaking for certain medical schools and research institutions that were incapable of doing any genuine cancer research. Second, it was sustained by a superstitious belief in a grossly unscientific notion: mice are miniature men…in sum, from the standpoint of current scientific theory of cancer, the whole mystique of the animal model systems is hardly more than superstitious nonsense…the moral is that animal model systems not only kill animals, they also kill humans. There is no good factual evidence to show the use of animals in cancer research has led to the prevention or cure of a single human cancer.
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Change is needed. Thirty years of experience with subcutaneous xenografts, human tumors implanted under the skin of the mouse, have satisfied few because so many drugs that cure cancer in these mice fail to help humans. A 2004 analysis in the Journal of the American Medical Association showed that only 3.8% of patients in phase I cancer drug trials between 1991 and 2002 achieved an objective clinical response — and the response rate is declining. Almost all drugs tried in humans work against subcutaneous xenografts in mice. “How many more negative data do you want? It’s very depressing.”
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The fundamental problem in drug discovery for cancer is that the model systems are not predictive at all. ancer research at Merck Research Laboratories in West Point, Pennsylvania…Researchers blamed the failures on the fact that the drugs were being tested against mouse, not human, tumors… the xenograft tumors don't behave like naturally occurring tumors in humans – they don't spread to other tissues, for example. Thus, drugs tested in the xenografts appeared effective but worked poorly in humans.
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Just as DNA chips revolutionized genome analysis, we hope to make cell chips (self-assembled arrays of cells on a thumbnail-sized chip) using our DNA-based cell adhesion strategy. Cell chips could be used as biosensors for detecting the presence of pathogens, or for drug screening, just to name of a few of the many possibilities.
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In Tamoxifen’s case, a drug first developed as a potential contraceptive languished for many years before its present application was found. Furthermore, its propensity to cause liver tumours in rats, a toxicity problem that thankfully does not carry over into humans, was not detected until after the drug had been on the market for many years. If it had been found in preclinical testing, the drug would almost certainly have been withdrawn from the pipeline.
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The moral authority of our most cherished institutions comes from their voluntary nature: the value of advice from a priest, a teacher or a loved one depends in large part on the fact that we are free to ignore it. But judges' pieces of 'advice' are court orders, enforceable ultimately by the raw physical power of imprisonment. It is precisely because of the awesomely enforceable nature of our powers that we must be so circumspect in exercising them. It is one thing for a co-worker, family member, doctor, or clergyman to confront someone about a perceived drug problem; it is quite another thing for a judge to compel drug treatment. Drug courts not only fail to recognize this important institutional distinction, but their very purpose is to obliterate it.
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Addiction should never be treated as a crime. It has to be treated as a health problem. We do not send alcoholics to jail in this country. Over 500,000 people are in our jails who are nonviolent drug users.
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I was in the drug store the other day trying to get a cold medication... Not easy. There's an entire wall of products you need. You stand there going, Well, this one is quick acting but this is long lasting...Which is more important, the present or the future?
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Expecting a carjacker or rapist or drug pusher to care that his possession or use of a gun is unlawful is like expecting a terrorist to care that his car bomb is taking up two parking spaces.
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My thinking tends to be libertarian. That is, I oppose intrusions of the state into the private realm -- as in abortion, sodomy, prostitution, pornography, drug use, or suicide, all of which I would strongly defend as matters of free choice in a representative democracy.
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Clearly, some time ago makers and consumers of American junk food passed jointly through some kind of sensibility barrier in the endless quest for new taste sensations. Now they are a little like those desperate junkies who have tried every known drug and are finally reduced to mainlining toilet bowl cleanser in an effort to get still higher.
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These are people who are unable to work because of mental or physical problems or drug or alcohol addiction.
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The Christian's Bible is a drug store. Its contents remain the same, but the medical practice changes.
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If drugs were tested properly using true scientific methods, the vast majority of them would not be allowed onto the market because their harmfulness and ineffectiveness would be all too apparent. The constant stream of new drugs would slow to a trickle and within a few years most drug companies would go bankrupt.
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Everything is a dangerous drug except reality, which is unendurable.
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Alcohol and drug addiction are problems, and we should use outside agencies that know the business. They do business all over the country. Why don't we contract them to do it? See, we should be in certain businesses.
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Drug addiction is no different from any other religion - sometimes the ritual is all that matters.
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When you want to save money for seniors, that may mean smaller profits for drug stores.
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A drug is neither moral nor immoral -- it's a chemical compound. The compound itself is not a menace to society until a human being treats it as if consumption bestowed a temporary license to act like an asshole.
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No drug, not even alcohol, causes the fundamental ills of society. If we're looking for the sources of our troubles, we shouldn't test people for drugs, we should test them for stupidity, ignorance, greed and love of power.
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Money is the new drug.
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Governor Rell believes we should not give one foot of ground to potential drug dealers.
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A strong positive mental attitude will create more miracles than any wonder drug.
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